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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCG
All Species:
13.64
Human Site:
T568
Identified Species:
33.33
UniProt:
O15287
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15287
NP_004620.1
622
68554
T568
L
D
R
R
D
E
A
T
A
L
W
W
R
L
E
Chimpanzee
Pan troglodytes
XP_520551
622
68533
T568
L
D
R
R
D
E
A
T
A
L
W
W
R
L
E
Rhesus Macaque
Macaca mulatta
XP_001091966
622
68585
T568
L
D
R
R
D
E
A
T
A
L
W
W
R
L
E
Dog
Lupus familis
XP_854703
806
88753
S752
M
D
R
R
D
E
A
S
A
L
W
W
R
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQR6
623
68487
E569
K
R
L
D
R
K
N
E
A
S
A
F
W
R
E
Rat
Rattus norvegicus
XP_001076851
623
68404
E569
K
R
L
D
R
K
N
E
A
S
A
F
W
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520423
598
65280
V540
L
N
R
R
P
E
A
V
A
H
W
R
E
L
E
Chicken
Gallus gallus
NP_989709
648
71724
A588
L
N
R
K
E
E
A
A
D
Y
W
Q
K
Y
L
Frog
Xenopus laevis
NP_001098745
640
71329
G581
L
G
R
R
T
E
A
G
S
Y
L
K
R
Y
Q
Zebra Danio
Brachydanio rerio
NP_991202
617
69657
E563
L
W
R
L
D
R
R
E
E
A
L
A
H
W
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.1
62.9
N.A.
72.5
71.7
N.A.
34.7
36.1
35.3
31
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
97.1
67.9
N.A.
81.5
81
N.A.
46.9
53
52
49.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
13.3
13.3
N.A.
60
33.3
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
66.6
60
53.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
70
10
70
10
20
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
40
0
20
50
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
70
0
30
10
0
0
0
10
0
70
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
0
0
10
0
20
0
0
0
0
0
10
10
0
0
% K
% Leu:
70
0
20
10
0
0
0
0
0
40
20
0
0
50
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
20
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% Q
% Arg:
0
20
80
60
20
10
10
0
0
0
0
10
50
20
10
% R
% Ser:
0
0
0
0
0
0
0
10
10
20
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
30
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
60
40
20
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
20
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _